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Asleep: The Forgotten Epidemic that Remains One of Medicine's Greatest Mysteries, by Molly Caldwell Crosby
Download PDF Asleep: The Forgotten Epidemic that Remains One of Medicine's Greatest Mysteries, by Molly Caldwell Crosby
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A fascinating look at a bizarre, forgotten epidemic from the national bestselling author of The American Plague.
In 1918, a world war raged, and a lethal strain of influenza circled the globe. In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it spread worldwide, leaving millions dead or locked in institutions. Then, in 1927, it disappeared as suddenly as it arrived.
Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and asylums as they try to solve this epidemic and treat its victims-who learned the worst fate was not dying of it, but surviving it.
- Sales Rank: #451891 in Books
- Published on: 2011-02-01
- Released on: 2011-02-01
- Original language: English
- Number of items: 1
- Dimensions: 8.30" h x .80" w x 5.50" l, .64 pounds
- Binding: Paperback
- 320 pages
- ISBN13: 9780425238738
- Condition: New
- Notes: BRAND NEW FROM PUBLISHER! 100% Satisfaction Guarantee. Tracking provided on most orders. Buy with Confidence! Millions of books sold!
From Booklist
On the heels of World War I, another atrocity emerged to take millions more lives: flu. Overshadowed by that worldwide viral menace was an equally—indeed, Crosby believes, an even more—frightening killer, encephalitis lethargica (EL). If the name rings no bell, perhaps that isn’t surprising, since the malady claimed “only” a million lives, though it left at least that many more permanently disabled, before dropping off epidemiologists’ maps around 1927. The illness’ popular moniker, sleeping sickness, is more familiar, to the point of seeming innocuous. But the disease was and is anything but. No one has ever been able to articulate its etiology. Just because it flared up during a flu pandemic doesn’t mean it is linked to flu by either causation or correlation. Yet the concurrence cannot be discounted. What’s more, the disease is unpredictable, having re-emerged a couple times since the 1920s. Crosby and others fear EL may return simultaneously with another worldwide outbreak of flu. Medical science is, they insist, no better prepared for it than it was 90 years ago. --Donna Chavez
Review
"Molly Crosby has provided a brilliant and deeply moving account of the fearful years between 1915 and 1927, when this mysterious, worldwide pandemic struck, giving us vivid, intensely human portraits..." - Oliver Sacks, author of Awakenings
"Here's medical curiosity combining history, mystery, and riveting storytelling..." - Publishers Weekly
"The engaging story of the outbreak of a bizarre disease...Crosby is a fine storyteller, peppering her case studies with facts about the history of neurology and details about 1910s New York." - Kirkus Reviews
"Harrowing..." - Discover magazine
"...a moving nonfiction account of a complicated disease." - Dallas Morning News
From the Author
This is a "forgotten" epidemic, lost amid the history of World War I, the massive flu pandemic of 1918, and the colorful 1920s, but for me, it was a more personal story. My grandmother was 16-years-old when she contracted "sleeping sickness" or encephalitis lethargica. She slept for 180 days and was never able to finish school. She survived, but with lifelong consequences. Hers was one of the better outcomes. As I learned in researching and writing this book, there is a far darker history to this tragic, unsolved medical mystery.
Most helpful customer reviews
35 of 36 people found the following review helpful.
"Death wasn't the worst fate."
By E. Bukowsky
Molly Caldwell Crosby's "Asleep," traces a strange malady whose origins are shrouded in mystery. Encephalitis lethargica ("a swelling of the brain that makes one sleepy") "came in two waves--the first began in 1916 and peaked in 1920." A second wave struck in 1924. Today, few people remember this scourge that killed close to a million people all over the world. One of the afflicted was Crosby's grandmother, Virginia Thompson Brownlee, who became ill in 1929 at the age of sixteen but was fortunate enough to survive with limited long-term effects. Tragically, many of the victims were children and young adults whose brains were not yet fully developed; they were not all equipped, physically or emotionally, to battle this destructive illness.
Although the symptoms of encephalitis lethargica varied from one individual to the next, some of the manifestations were: disconnectedness from one's body, lethargy, delirium, slurred speech, stiffness, seizures, tics, Parkinsonism, and extreme personality changes. Some people became catatonic or went into a deep sleep for long periods of time. Around one third recovered, one third died, and one third survived. However, some became so disabled that they were permanently institutionalized. One common thread is that many of the sufferers had recovered from the flu before they came down with encephalitis lethargica. Even those who appeared to have recovered fully were vulnerable to recurrences years later. It was almost as if a demon lay dormant in their bodies, only to reemerge when they least expected it.
Crosby divides her book into seven chapters, each of which recounts a compelling case history, including that of Jessie Morgan, the wife of financier J. P. Morgan. In addition, the author explores the careers of prominent physicians who cared for patients with this ailment. Enhancing the narrative are richly described details of the social, cultural, medical, and political climate that served as a backdrop for the pandemic. Crosby puts encephalitis lethargica in context as she recounts the horrors of World War I, the influenza outbreak that killed more than twenty million people, the building boom in New York City, the amazing technological developments of the 1920's, the Stock Market Crash, the Great Depression, advances in neuropsychiatry, epidemiology, and public health, and the construction of new facilities to house the mentally ill.
Theories abound, but to this day no one knows what causes encephalitis lethargica. Oliver Sacks, the renowned writer and neurologist who wrote about his work with encephalitis patients in "Awakenings," asserts that "this strange, often terrible disease is not extinct, only quiescent. It may well strike again in our lifetimes." "Asleep" reads like a riveting novel that one wishes were merely a nightmare invented by an imaginative writer. Unfortunately, it is all too real. Crosby's facts are meticulously documented; she includes photographs, extensive endnotes, a lengthy bibliography, and a thorough index. This is a beautifully written, lucid, multilayered, and unforgettable work of non-fiction.
14 of 14 people found the following review helpful.
"Asleep" sheds light on family mystery
By J. A. Monfort
An interview on NPR alerted me to Ms. Crosby's book. I, too, had a grandmother diagnosed and recovered from sleeping sickness. Crosby's investigation shed light on how this disease affected families and how victims were trapped in their own bodies. Having grown up in an era where children didn't ask probing questions of family members, I found this to be a book worth sharing with siblings.
7 of 7 people found the following review helpful.
An Overdue Look at a Devastating Syndrome
By R. Schultz
Ever since I read Oliver Sacks' fascinating book "Awakenings" about the decades-long deep-freeze that some victims of the 1920's epidemic of encephalitis had been put into - I'd been hoping to find some follow-up book about sleeping sickness itself. Here is that book.
Author Molly Crosby traces some of the history of the disease of encephalitis lethargica (alternately known as "sleeping sickness). She paints a picture of the early part of this century and how World War I, with the crowded, transient conditions it promoted, allowed this strange disease to get a foothold in many urban areas around the world. We're transported back to the New York of the 1920's, its chestnut vendors, trolleys, tenements. We're advanced through some of the Depression years. Crosby includes some astute economic analysis here, finding remarkable parallels between the kinds of indebtedness that triggered the 1929 Depression and our current recession. So this book offers the bonus of providing some very interesting general history about an eventful couple of decades.
The epidemic occurred in the wake of the much more widely documented influenza epidemic of 1918. The Doctors and other medical researchers who devoted themselves to the disease back then were baffled at every turn by the strange twists and turns that this lesser-known companion disease of influenza was capable of taking. Ultimately, the medical community was so frustrated by the disease's inscrutable, protean nature, that when it receded as far as being epidemic - it was shelved and almost forgotten. Crosby returns us to the heyday of encephalitis research.
This is generally a very readable, authoritative look at the frightening disease and its often long-lasting effects on the personalities and physical possibilities of its victims. However, one fault with the organization of this book is that it waits until Page 166 to define "encephalitis." It turns out that "encephalitis" by itself is a generic term that can refer to any swelling of particular key areas of the brain. Any number of diseases can result in this inflammation - including meningitis, herpes, and even measles. But the specific kind of encephalitis being examined here, the encephalitis lethargica or the disease that caused prolonged sleep disturbance, is considered a distinct entity. It might have been a good idea for Crosby to provide this explanation early in the book in order to orient readers better in the physiology of her subject.
I would also have liked to read more about current efforts to pinpoint the cause of the disease. Crosby only devotes a brief final chapter to viral causes that have been ruled out - and to the strep throat germ that is being vaguely implicated. Even though the disease remains a mystery, I'd have appreciated more details about such modern researches.
Either way though, this is an important book with profound implications for how we look at both mental and physical illness and the connection between the two. Whatever microscopic agent turns out to be the cause of the illness has the power to profoundly transform whomever it infects. Some feel that many classic fairytales as well as many modern horror stories, spanning fictions from "Sleeping Beauty" to "Dr. Caligari's Cabinet" and a myriad of our zombie tales were probably based on the all-too-real, bizarre symptoms evoked by sleeping sickness. Physically, the disease often produces many of the symptoms of Parkinson's. Emotionally, it has the power to turn previously sane, amiable people into individuals plagued by various forms of obsessive-compulsive disorder, as well as by uncontrollable impulses toward self-mutilation and homicidal rage.
So this book, even though it is about a disease that crested back in the 1920's, is as relevant as today's headlines.
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